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The StabilOx System is your turn-key solution; it combines the advantages of StabilOx® Oxygen Absorbing Packets or Canisters with the proven reliability of our corresponding APA-series dispensing equipment. StabilOx® Packets and Canisters are designed to reduce package headspace oxygen levels while managing headspace moisture and drug product free moisture, resulting in the reduction or elimination of oxidative degradation. StabilOx Packet and Canister Dispensers are compatible with a variety of packaging line configurations, including bottling lines, horizontal flow wrappers, VFFS, thermoformed pouching, and other layouts. The dispensers are made using only the highest quality sensors, drive mechanisms, and cutters. All of these capabilities add up to higher efficiencies for your packaging operations.
Achieving stability in pharmaceutical formulations or medical devices requires a difficult balance between increasingly complex variables. Success is vital to a new drug reaching the marketplace. StabilOx Packets and Canisters help achieve this without toxic packaging components or expensive drug product formulation changes. StabilOx Packets and Canisters provide a simple solution that resides inside the packaging instead of, for example, an additive to the drug product itself.
Traditional pharmaceutical-safe, inorganic oxygen absorbers rely on the irreversible oxidation of the sorbent material. Since the reaction requires moisture, the moisture must be provided in the packet or canister itself, the product, or from the package environment.
StabilOx Packets and Canisters provide their own moisture to initialize the oxygen removal process from the package. It then relies on package moisture ingress for continued oxygen absorption while establishing an optimal Equilibrium Relative Humidity (ERH) in the package headspace. This is critical in retaining drug performance, stability, and integrity.
StabilOx Packet and Canister Dispensers offer accurate reliable sorbent dispensing. The dispensers are configurable to meet your needs (e.g. packet size, bottle size, multiple drops), and with speeds up to 300 packets per minute, StabilOx Packet and Canister Dispensers are among the fastest most accurate systems available.
StabilOx Packets and Canisters contribute to the stability profile / shelf life of many products within their packaging. Consequently, the packets’ or canisters’ capacity must be protected during packaging operations to prevent capacity loss. Like no other dispensers available, our APA series of StabilOx Packet Dispensers are available with packet spool supply systems that are offer optional automated nitrogen purge with related nitrogen supply and oxygen level monitoring / alarming (to the PLC). Our APA-9000 Canister Dispenser is available with nitrogen purge and feature first in / first out (FIFO) control by use of alternately running hoppers. Dispensers include: